Brain signatures of OCD: In collaboration with OCD experts across five countries, we are using imaging methods to examine multiple brain circuits thought to underlie OCD behavior. Identifying brain signatures of OCD will provide robust new treatment targets and help pave the way to precision psychiatry where individual brain signatures can help guide treatment choices.
Precision Medicine for OCD: In a collaboration with the Institute of Genomic Medicine, the Center for OCD and Related Disorders is looking at the genes of individuals with OCD to see if we can identify genes that may have put those individuals at risk for OCD. This study seeks to identify genes that may explain why an individual developed OCD and to identify which treatments might work best for them.
Novel therapeutics: We have partnered with Biohaven Pharmaceuticals to investigate the efficacy of a novel medication that affects the brain’s glutamate system. We are seeking individuals with OCD who are taking an SRI, and still experiencing clinically significant symptoms.
State-of-the-art technology: In collaboration with nOCD, we are investigating the feasibility of a mobile application for cognitive behavioral therapy. With therapist guidance, individuals with OCD can access support and therapeutic techniques on the go from their phone.