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The OCD research program is dedicated to the mission of improving the lives of people with obsessive-compulsive disorder (OCD) and related disorders by conducting cutting edge research to transform how we understand and treat these disorders. For the patients of today, we examine how to combine and sequence current treatments to maximize outcome, and we explore novel treatments. For the patients of tomorrow, we collaborate with experts in neuroimaging, genetics, and basic science to examine what causes obsessions and compulsions. Below is a list of our current research opportunities.

If you are interested in participating in our research visit, https://redcap.link/bk7i8wri. To learn more about specific research studies, visit our website www.columbiapsychiatry.org/ocd.

 

Research Studies

Brain Signatures of OCD: In collaboration with OCD experts across five countries, we are using imaging methods to examine multiple brain circuits thought to underlie OCD behavior. Identifying brain signatures of OCD will provide robust new treatment targets and help pave the way to precision psychiatry where individual brain signatures can help guide treatment choices.

Brain Signatures of Unaffected Siblings of People with OCD: The Center for OCD and Related Disorders is working hard to better understand the brain circuits involved in OCD. As part of this research, we are recruiting adult siblings of people with OCD to help us learn about how the brain makes some people more likely and others less likely to develop OCD symptoms. Are you able to come to New York City for one day to help us advance this science? Everything else can be done remotely. You will be compensated for your time. Click here for more information about this study.

Precision Medicine for OCD: In a collaboration with the Institute of Genomic Medicine, the Center for OCD and Related Disorders is looking at the genes of individuals with OCD to see if we can identify genes that may have put those individuals at risk for OCD. This study seeks to identify genes that may explain why an individual developed OCD and to identify which treatments might work best for them.

If you are interested in participating in our research visit, https://redcap.link/bk7i8wri. To learn more about specific research studies, visit our website www.columbiapsychiatry.org/ocd.

 

 

Publications on the Quality of Care in OCD

Treatment of Obsessive Compulsive Disorder in a Nationwide Survey of Office Based Practice: 

This study examined what treatments adults with OCD receive during treatment visits to U.S. office based physicians. Among the 316 visits examined, most were treated with psychotropic medications (84%), most commonly Serotonin Reuptake Inhibitors (69%) and less commonly psychotherapy (39%).

Patient Preferences and Acceptability of Novel Treatment for Obsessive Compulsive Disorder: 

This study examine preferences for and acceptability of treatments for OCD. Among 216 adults with moderate OCD symptoms, preferences for exposure and response prevention and medications were similar (55% and 45% respectively). Participants preferred the addition of exposure and response prevention over additional medications if they were still experiencing symptoms on medication for OCD.

Acceptability, Feasibility, and Effectiveness of Internet-Based Cognitive-Behavioral Therapy for Obsessive-Compulsive Disorder in New York: 

This study examined if an Internet Based Treatment (based on exposure and response prevention) program for OCD is acceptable, feasible and effective. In 40 adults with moderate to severe OCD, we found that the treatment program was effective in reducing OCD symptoms and symptoms of depression and improving quality of life. Participants found the program acceptable and it was feasible to implement.

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